The ENSA Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Ensa. This antibody recognizes Human, Mouse, and Rat antigen. The ENSA Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase (By similarity). Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K (ATP) channel currents